Fen Bilimleri Enstitüsü: Recent submissions

  • Investigation of effects of neurological diseases on human brain metabolism: computational systems biology approach 
    Sertbaş, Mustafa. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    The objective of this study is the investigation of the effects of Parkinson’s disease on human brain metabolism by using computational systems biology approach. A new brain metabolic model originated from Çakır et al., ...
  • Investigation of dynamic allostery in motor proteins 
    Kaya, Cihan. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    Allostery is a key concept in regulation of protein function. The communication pathways which are equivalent of the allosteric signaling or energy propagation pathways are the most significant aspect of allosteric mechanism. ...
  • Design and characterization of polymer-fullerene bulk heterojunction solar cells 
    Solak, Selen. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    Design and characterization of polymer-fullerene bulk heterojunction solar cells were experimentally studied in this study. In the experiments, ITO or highly conductive PEDOT:PSS coated glasses were used as anode, P3HT and ...
  • Oxidative steam reforming of light hydrocarbons in a catalytic microchannel reactor 
    Şen, İrem. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    Oxidative steam reforming (OSR) reaction of light hydrocarbons (methane and propane) is investigated under exhaust gas reforming (EGR) conditions in a catalytic heat-exchange integrated microchannel by computational and ...
  • An in silico study on ribosome-binding trigger factor 
    Can, Mehmet Tarık. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    The trigger factor protein (TF), unique to bacterial organisms, binds to ribosome tunnel mouth and works as a chaperone in helping the nascent chains emerging from the ribosome tunnel to acquire their native fold. A 500 ...
  • Neural networks analysis of water gas shift reactions over nobel metal catalysts using published data in literature 
    Odabaşı, Çağla. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    The aim of this thesis is to apply the machine learning methodologies for knowledge extraction from experimental data for water gas shift reaction over noble metal catalysts from the papers published in the literature to ...
  • Catalytic oxidation of methane in a microchannel reactor under oxygen-lean conditions 
    Kara, İsmail Bahadır. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    The aim of this study is to investigate methane oxidation in a microchannel reactor under the effect of Pt, Rh and Ru catalysts supported on δ-Al2O3. Methane oxidation is an integrated part of the oxidative steam reforming ...
  • Modeling and simulation of oxidative coupling of methane in a heat-exchange integrated microchannel reactor 
    Tezcan, Funda İdil. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    Oxidative coupling of methane (OCM) involves catalytic conversion of methane into C2 hydrocarbons (ethane and ethylene) and offers an alternative oil-free production of important feedstock used in petrochemical industry. ...
  • Identification of PTP1B dynamics using frequency response analysis 
    Eren, Dilek. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Protein tyrosine phosphatase 1B (PTP1B) plays a key role as negative regulator of insulin and leptin signaling. In human PTP1B, a significant conformation change is seen in the WPD loop from open (inactive) to closed ...
  • Data compression and reconstruction in process engineering applications 
    Önol, Ceyda. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Recent improvements in sensor technology have resulted in huge amount of measured process data along with the increasing need for compression prior to storage. Hence, efficient process data compression and reconstruction ...
  • Gas chromatographic study of hydrogen and hydrocarbon adsorption on platinum/alumina catalyst 
    Gönenç, Z. Sermin. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1985., 1985.)
    The irreversible and the reversible adsorption of hydrogen on commercial 0.3%wt Pt/Aı2O3 reforming catalyst has been studied in a gas-solid chromatograph in the temperature range 74-233 °C and 96-237 °C respectively. The ...
  • Constrained neural networks 
    Özer, Ümit. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
  • Virtual screening and docking of potential protein kinase B inhibitors 
    Kenar, Seval. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    This study aims to carry out a molecular docking process of novel ATP competitive inhibitors for protein kinase B-beta (PKBβ / AKT-2), activation of which has been observed in 30-40% of ovarian and pancreatic cancers. 3D ...
  • A DFT study on interaction between Au, Re and Au-Re surfaces with species involved in WGS reaction 
    Uzun, Ali. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    In this study, the steps of WGS reaction was investigated through studying the adsorption/co-adsorption of its reactants, products and possible intermediate species on Au(111), Re(001) and Au-Re(001) surfaces at atomic ...
  • Three dimensional modeling of autothermal reforming of methane in a Pt-Ni washcoated micro-channel reactor 
    Aksakal, Kerem. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Steady state behavior of hydrogen production from oxidative steam reforming of methane in a Pt-Ni bimetallic washcoated Al2O3 microchannel reactor was modeled and simulated three dimensionally by using CFD program. Internal ...
  • Beta-lactamase ligand recognition 
    Menekşedağ, Deniz. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Beta-lactamases hydrolyze the beta-lactam ring of antibiotics, rendering them ineffective. Understanding the inhibitor recognition mechanism of beta-lactamases will give important information toward the fight against ...
  • Multiple and alternate optima of LP problems via recursive MILP : a MATLAB implementation 
    Sayın, Ridade. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    In this thesis, the Recursive Mixed Integer Linear Programming (RMILP) algorithm invented by Prof. Grossman's group at the Carnegie Mellon University is studied. The algorithm is guaranteed to find all the alternate optima ...
  • Causality in time series : dynamic time warping versus granger causality 
    Yallak, Leyla Zeynep. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Causality is a concept studied in various areas such as economics, and engineering. Identifying the cause and effect relations among variables is important as it enables the control of the effected variable by the variation ...
  • Effect of simultaneous beta-lactamase inhibitor protein expression on cellular beta-lactamase activity 
    Yalaz, Kadriye Simay. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    β-lactam antibiotics are commonly used in the treatment of bacterial infections. However, due to underuse and misuse of β-lactam antibiotics, bacteria have developed mechanisms that counteract β-lactam antibiotics. The ...
  • Analysis of cracking phenomena along conformational transition pathways of proteins 
    Meriçer, Çağlar. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    The weighted ensemble (WE) methodology was incorporated into an iterative ANM-MC (Anisotropic network model- Monte Carlo) simulation algorithm, which has been developed to generating targeted conformational transition ...