Fen Bilimleri Enstitüsü: Recent submissions

  • Liposomes for encapsulating drugs and complexing DNA 
    Çağdaş, Fatma Melis. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    Surface-active substances, amphiphiles, show the ability of self-organization in solvents, forming self-assemblies with a large variety of morphologically different structures. One of these structures is liposomes, formed ...
  • Experimental and computational investigation of structure- reactivity relationship of methacrylates 
    Karahan, Özlem. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    In the first part of this work, a series of alkyl α-hydroxymethacrylates (RHMA) were synthesized and computationally modeled in order to understand the structure-reactivity relationships in their polymerizations. Several ...
  • Synthesis of axially chiral thiazolidine derivatives and their atroposelective reactions 
    Erol, Şule. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    In this study, various axially chiral thiazolidine-4-one and 4-thiones and their corresponding 5-benzylidene derivatives were synthesized in which the N3(sp2)-Carylbond rotation is hindered and used as scaffolds for the ...
  • Chain extension reactions of unsaturated polyesters using difunctional molecules 
    Taylan, Ediz. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    In this study the effectiveness of various chain extenders in increasing the molecular weight of unsaturated polyesters was investigated. For this purpose eight different chain extenders (with di or multi-functionalities) ...
  • Conformational analysis of 2-substituted cyclohexanone ketal derivatives by molecular mechanics and nuclear magnetic resonance 
    Varnalı, Tereza. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1986., 1986.)
    The present study is concerned with the application of the Molecular Mechanics Method to 2-substituted cyclohexanoneketals. The object is to find the conformational free energy difference between the equilibrating conformers ...
  • A computational approach the free radical polymerization of acrylates and methacrylates 
    Değirmenci, İsa. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    Free radical polymerization (FRP) is one of the most favorable chemical reactions employed in both industry- and laboratory-scale chemical productions, because it can convert a wide variety of vinyl monomers into high ...
  • Polymerization reactions of functionalized vegetable oils with petroleum-based macromonomers 
    Öztürk, Cem. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    The aim of this work is to synthesize new polymers from plant oils. Polymerization of plant oil triglycerides is possible by attaching a polymerizable group to the triglyceride. This strategy has been used by us and by ...
  • Axialy chiral n-(o-aryl)-2-thioxo-oxazolidine-4-one and rhodanine derivatives: enantiomeric separation and determination of racemization barriers 
    Yılmaz, Esra Müjde. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    In this study, sterically hindered 5,5-dimethyl-3-(o-aryl)-2-thioxo-4-oxazolidinones, 5,5-dimethyl-3-(o-aryl)-2-thioxo-4-thiazolidinones and 3-(o-aryl)-2-thioxo-4- thiazolidinones(rhodanines) have been synthesized as ...
  • Modeling the selectivity in pericyclic reactions 
    Ölçüm, Nihan Çelebi. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2009., 2009.)
    Pericyclic reactions are very powerful and widely utilized transformations to obtain complex molecules. The selective versions have received remarkable interest and have found extensive use in synthetic organic chemistry ...
  • A hybrid computational approach to the benzoin synthesis in different media 
    Topal, Kevser Göçmen. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    Benzoin derivatives are widely used in organic chemistry, mainly as starting materials in drug synthesis and photoinitiators in polymer chemistry, due to their bifunctionality, the presence of the asymmetric center, and ...
  • Chemical characterization of lipid residues in neolithic and chalcolithic pottery from Anatolia 
    Bıyık, Ayla Türkekul. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2009., 2009.)
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  • Elucidation of the deamidation mechanism of asparaginyl residues in peptides and proteins 
    Çatak, Şaron. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    Demidation of proteins is a topic of wide interest that has been subject to experimental and theoretical studies. Deamidation is a nonenzymatic and spontaneous process that converta asparagine conformational changes in ...
  • Asymmetric syntheses, ring opening and stereoselective reactions, absolute conformation and activation barrier determinations on axially chiral oxazolidine derivatives 
    Ordu, Öznur Demir. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    In this study, sterically hindered 5-methyl-3-(o-aryl)-2,4-oxazolidinediones, 5-methyl- 3-(o-iodophenyl)-2-thioxo-4-oxazolidinedione and 5,5-dimethyl-3-(o-aryl)-2,4- oxazolidinediones have been synthesized. Diastereomeric ...
  • Functionalization and polymerization of plant oil triglycerides 
    Çaylı, Gökhan. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    In this study, new polymers and were synthesized from different plant oil triglycerides by using allylic groups of the triglycerides. Moreover, allylic positions and double bonds of soybean oil were used for preparation ...
  • An investigation of the carbon-carbon bond rupture in fluoroethanes by RRKM theory 
    Aviyente, Viktorya. (Thesis (Ph.D.)- Bogazici University. Institute for Graduate Studies in Social Sciences, 1983., 1983.)
    In this dissertation, the thermal decompositions of ethane, 1,1,2,2-tetrafl uoroethane, pentafl uoroethane and hexafl uoroethane have been subjected to a theoretical treatment i n terms of the quantum statistical RRKM ...
  • Modeling the solvent effect in free radical polymerization and deamidation of peptides 
    Doğan, Berna. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    In the first part of this study, the kinetics free radical polymerization of ethyl methacrylate (EMA) and ethyl α-hydroxy methacrylate (EHMA) in solution is investigated; in the second part the deamidation in three different ...
  • Polymer - dendron based micelles as drug delivery systems 
    Bilgen, Nuray. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Polymeric micelles are remarkable nominees for drug delivery systems due to their excellent biocompatibility also they provide high loading capacity to hydrophobic inner core and increase drug solubility. In water, micelles ...
  • Modeling stereoselective reactions in solution 
    Yıldırım, Aslı. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    In this study, ring-chain-ring tautomerization and asymmetric desymmetrization reactions are investigated by taking the solvent effect into account. In the first part, ring-chain-ring tautomerization mechanism is investigated ...
  • Synthesis, HPLC and NMR studies on axially chiral pyridine compounds as potential bidentate N,N'-ligands 
    Işıkgör, Furkan Halis. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    In this study, axially chiral enantiomeric and diastereomeric 2-arylimino-3-aryl-thiazolidine-4-ones have been synthesized and their stereostructures have been investigated. In these compounds, the rotation around N3-aryl ...
  • A computational approach to the core of eunicellins 
    Bozkurt, Esra. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    The asymmetric Diels-Alder reaction has attracted much interest for decades. Most recently, interest in the use of catalysts in cycloadditions has gained momentum due to their capacity to provide complex stereoselectivity ...