Kimya: Recent submissions

  • Maleimide based thiol reactive hydrogels and polymers from orthogonally functionalizable biodegradable dendrons 
    Onbulak, Sebla. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    Hydrogels and polymers with reactive side chains have gained an increased attention in recent years due to their amenability to efficient post-functionalization. Wide applications of such hydrogels and polymers in biomedical ...
  • Photofunctionalizable hydrogels via orthogonally clickable dendrons 
    Yiğit, Sezin. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    Hydrogels are three-dimensional, cross linked hydrophilic polymeric materials that have attracted much attention due to their key role in the development of drug delivery systems, biomolecular sensors and scaffolds for ...
  • Synthesis, characterization, micellar and drug release properties of dihydrophilic / amphiphilic poly (n-isoproplacrylamide) -b-poly (vinyl acetate )/ poly (vinyl alcohol) diblock copolymers 
    Helvacıoğlu, Ekmel. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    In this study, poly(vinyl acetate)-b-poly(N-isopropylacrylamide) block copolymers, which were previously synthesized by macromolecular design via interchange of xanthates (MADIX) process, are partially or fully hydrolyzed ...
  • Modeling cycloaddition reactions 
    Agopcan, Sesil. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    In this study, the selectivities in two types of cycloaddition reactions, namely Diels- Alder and 1,3-dipolar cycloadditions are investigated. In the first part, the diastereoselectivity in the hydrogen bonding assisted ...
  • Synthesis of branched alkyl substituted potential drug molecules active against prostate cancer 
    Çavuşoğlu, Nariye. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    Prostate cancer is the second most common malignancy and age related cause of death among males especially in the western world. It is claimed that there is a relation between the probability of getting prostate cancer and ...
  • Thermally cleavable multiarm and miktoarm star polymers via Diels-Alder / retro Diels-Alder strategy 
    Munkhbat, Oyuntuya. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    Diels-Alder reaction is a well known [4+2] cycloaddition reaction between a diene and a dienophile. The fact that Diels-Alder reaction takes place even at room temperature without use of any other reagents and reverse ...
  • Dendron-polymer-dendron based micelles as drug delivery systems 
    Manavoğlu, Emine Ece. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    Polymeric micelles are known to be good candidates for drug release systems due to their high loading capacities of inner hydrophobic core as well as unique compatibility in the body. Micelles from amphiphilic copolymers ...
  • Synthesis of end-functionalized alkyl α-(hydroxymethyl) acrylate ester ether dimer derived polymers via atom transfer radical polymerization 
    Ryskulova, Kanykei. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    In this research, end group modification, hydroxylation, of the cyclic polymers obtained by the atom transfer radical polymerization of the alkyl- α-(hydroxymethyl) acrylate ester dimers (RHMA) were targeted. The dimers ...
  • Heterogeneous photocatalytic activity of transition-metal cation impregnated TiO2 
    Rakshandeh (Bazargan), Parisa Deljouie. (Thesis (M.S.)- Bogazici University. Institute for Graduate Studies in Science and Engineering, 1993., 1993.)
    Irradiation of aqueous Ti02 dispersions containing metal ions with light of energy equal or greater than the bandgap of the catalyst. leads to a deposition on the semiconductor particle surface. This photodeposition process ...
  • Core reactive biodegradable multiarm star polymers 
    Kılıç, Elif. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    Functionalizable macromolecules have attracted increasing attention as polymeric materials due to their wide application in material and biological sciences. Although a lot of work has been done in this area, little attention ...
  • Molecular docking study for novel phosphodiesterase-IV inhibitors 
    Çifci, Gülşah. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    In this study, a molecular docking process for different Phosphodiesterase4 inhibitors is carried out. In the molecular modeling field, the process of docking a ligand to a binding site consists in mimicing the natural ...
  • Recognition mediated fabrication and tailoring of poymeric and colloidal microstructures 
    Yeşilbağ, Gülen. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    Molecular self-assembly is the spontaneous and reversible organization of molecular units into ordered structures by non-covalent interactions. Due to specific non-covalent interactions, the building blocks such as molecules, ...
  • Investigating the roles of important amino acid residues in GTPase activity of Elongation Factor-Tu (EF-Tu) 
    Gül, Şeref. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    A large number of guanosine triphosphate (GTP)/ guanosine diphosphate (GDP) binding proteins (G-proteins), which usually have intrinsic (and/or stimulated) GTPase activity, are involved in a wide range of cellular regulatory ...
  • Bone targeted photodynamic therapy 
    Demirci, Gönül. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    Photodynamic therapy (PDT) is a method for treatment of cancerous tumors and many other diseases. PDT is the preferential delivery of a photosensitizer (PS) to tumor tissue which is followed by irradiation of light of ...
  • Modeling the propagation, chain transfer and tacticity in free radical polymerization 
    Furuncuoğlu, Tuğba. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    In this study, the free radical polymerization of methyl methacrylate (MMA) and NIsopropylacrylamide (NIPAM) is investigated by using Density Funtional Theory (DFT). In the first part, the role of thiophenols as chain ...
  • Reactive polymers for life sciences 
    Genç, Tuğba. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    Synthesis of polymers with reactive side chains has attracted considerable attention since these polymers are widely utilized in bioengineering applications such as controlled drug delivery, wound dressing and tissue ...
  • Design and synthesis of drug molecules against prostate cancer 
    Şahin, Tuba. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    Prostate cancer is a common disease in today’s world; especially in the western world it is the most prevalent cancer among men. It is believed that there is a correlation between prostate cancer and increased levels of ...
  • Synthesis and microcontact molding of functionalizable hydrogels 
    Yapar, Serap. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    Hydrogels are crosslinked polymers that have large number of hydrophilic groups and capacity to hold water in their three dimensional network structure. These materials have a wide range of application in biomedical and ...
  • Anti-angiogenesis chemotherapy agents 
    Çıtak, Duygu. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    Angiogenesis can be explained as the growth of new blood vessels from pre-existing vasculature. It has an important and vital role in growth and development, as well as in wound healing. Anti-angiogenic substances suppress ...
  • Synthesis of angiogenesis inhibitors and their conjugation to macromolecules 
    Tanrıver, Gamze. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    Angiogenesis is a term used for formation of new blood vessels from pre-existing vessels. Normally, angiogenesis process is essential for wound healing yet, unregulated angiogenesis plays a pivotal role on tumor growth and ...

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