Kimya Mühendisliği: Recent submissions

  • Identification of PTP1B dynamics using frequency response analysis 
    Eren, Dilek. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Protein tyrosine phosphatase 1B (PTP1B) plays a key role as negative regulator of insulin and leptin signaling. In human PTP1B, a significant conformation change is seen in the WPD loop from open (inactive) to closed ...
  • Data compression and reconstruction in process engineering applications 
    Önol, Ceyda. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Recent improvements in sensor technology have resulted in huge amount of measured process data along with the increasing need for compression prior to storage. Hence, efficient process data compression and reconstruction ...
  • Gas chromatographic study of hydrogen and hydrocarbon adsorption on platinum/alumina catalyst 
    Gönenç, Z. Sermin. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1985., 1985.)
    The irreversible and the reversible adsorption of hydrogen on commercial 0.3%wt Pt/Aı2O3 reforming catalyst has been studied in a gas-solid chromatograph in the temperature range 74-233 °C and 96-237 °C respectively. The ...
  • Constrained neural networks 
    Özer, Ümit. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
  • Virtual screening and docking of potential protein kinase B inhibitors 
    Kenar, Seval. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    This study aims to carry out a molecular docking process of novel ATP competitive inhibitors for protein kinase B-beta (PKBβ / AKT-2), activation of which has been observed in 30-40% of ovarian and pancreatic cancers. 3D ...
  • A DFT study on interaction between Au, Re and Au-Re surfaces with species involved in WGS reaction 
    Uzun, Ali. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    In this study, the steps of WGS reaction was investigated through studying the adsorption/co-adsorption of its reactants, products and possible intermediate species on Au(111), Re(001) and Au-Re(001) surfaces at atomic ...
  • Three dimensional modeling of autothermal reforming of methane in a Pt-Ni washcoated micro-channel reactor 
    Aksakal, Kerem. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Steady state behavior of hydrogen production from oxidative steam reforming of methane in a Pt-Ni bimetallic washcoated Al2O3 microchannel reactor was modeled and simulated three dimensionally by using CFD program. Internal ...
  • Beta-lactamase ligand recognition 
    Menekşedağ, Deniz. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Beta-lactamases hydrolyze the beta-lactam ring of antibiotics, rendering them ineffective. Understanding the inhibitor recognition mechanism of beta-lactamases will give important information toward the fight against ...
  • Multiple and alternate optima of LP problems via recursive MILP : a MATLAB implementation 
    Sayın, Ridade. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    In this thesis, the Recursive Mixed Integer Linear Programming (RMILP) algorithm invented by Prof. Grossman's group at the Carnegie Mellon University is studied. The algorithm is guaranteed to find all the alternate optima ...
  • Causality in time series : dynamic time warping versus granger causality 
    Yallak, Leyla Zeynep. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Causality is a concept studied in various areas such as economics, and engineering. Identifying the cause and effect relations among variables is important as it enables the control of the effected variable by the variation ...
  • Effect of simultaneous beta-lactamase inhibitor protein expression on cellular beta-lactamase activity 
    Yalaz, Kadriye Simay. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    β-lactam antibiotics are commonly used in the treatment of bacterial infections. However, due to underuse and misuse of β-lactam antibiotics, bacteria have developed mechanisms that counteract β-lactam antibiotics. The ...
  • Analysis of cracking phenomena along conformational transition pathways of proteins 
    Meriçer, Çağlar. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    The weighted ensemble (WE) methodology was incorporated into an iterative ANM-MC (Anisotropic network model- Monte Carlo) simulation algorithm, which has been developed to generating targeted conformational transition ...
  • Effect of the direction of the electric field on the interfacial instability between a newtonian fluid and a viscoelastic polymer 
    Nurocak, Aybike. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Micro channels are widely used in many industrial applications as they offer the ability to work in small volumes, consume low energy and less time, and reduce costs. Another important application of microfluidics is to ...
  • A process variable study of apple pectin extraction 
    Dereboylu, E. Ayça. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1985., 1985.)
    Dried Amasya apple pomace was used for extraction of apple pectin in this process variable study. Process variables of the extraction process were chosen as extraction temperature, duration of the extraction and acidity ...
  • Understanding the membrane penetration of antimicrobial 
    Alaybeyoğlu, Begüm. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    The studies on β-lactam antibiotics have found great interest since the use of antimicrobial therapy became widespread and as a result, bacteria started to develop resistance against β-lactam antibiotics. The most effective ...
  • Optimal design under uncertainty via CVaR (conditional value at risk) 
    Kumbasar, Sıla. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    The aim of this thesis work is to investigate the possibility of controlling and (re)shaping the statistical probability distribution of optimal objective function values in optimization problems related to process synthesis, ...
  • Investigation of conformational fluctuations in protein dynamics: torsional Gaussian Network Model 
    Özbakır, Harun Ferit. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Elastic network models based on Normal Mode Analysis (NMA) are very useful in determining the conformational fluctuations that would affect the functions of proteins. Gaussian Network Model (GNM) is proved to be a very ...
  • Investigation of coupling between collective dynamics and function of enzymes 
    Kocaman, Duygu. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    To bridge the structure and function of an enzyme through dynamics is an important problem in protein science. For this aim, the vibrational dynamics for a set of enzymes with different biological units and fold types are ...
  • An experimental study on the effect of metal loadings on WGS performance of Au-Re system 
    Yoğurtçu, Burcu. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    The aim of the current work is to understand the effect of Au and Re loadings and Au:Re loading ratio on the WGS performance of the Au-Re/CeO2 system under the flow of realistic feeds. In this experimental work, water-gas ...
  • Functional analysis of the genes in the glucose metabolic network by a system based modular approach 
    Yüzüak, Okan. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    In this study, all proteins associated with the Process Gene Ontology (GO) term “Glucose Metabolic Process” were collected and a network of all reported interactions among these entities was constructed with a stringent ...