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Browsing Moleküler Biyoloji ve Genetik by Subject

Browsing Moleküler Biyoloji ve Genetik by Subject "Apoptosis."

Now showing items 1-7 of 7

Importance of ASC expression for melanoma tumorigenesis in vivo and a role for inflammasome activation in apoptosis induction

Çifdalöz, Metehan. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)

ASC is an adaptor protein which is capable of binding to numerous partners due to its two oligomerization domains, PYRIN and CARD. Its involvement in the inflammasome complex as an essential adaptor, in the regulation of ...
Importance of ASC expression levels in the development of chemoresistance in human melanoma cell lines

Erdoğan, Damla. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)

ASC (Apoptosis-associated speck like protein containing a CARD) is an adapter protein containing PYRIN and CARD interaction domains. ASC is implicated in apoptosis and innate immune signaling and is required for IL-1 and ...
In vivo studies of ASC specks as antigen delivery vehicles

Yaşa, Seda. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2016., 2016.)

ASC is a 22 kDa adapter protein which is an essential component of the NLRP3, NLRC4 and AIM2 in ammasome complexes. ASC has critical functions in in ammatory and pyroptotic signaling pathways via activating caspase-1. In ...
Investigation of homotypic PYD and CARD domain interactions in ASC speck assembly

Otaş, Hasan Ozan. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)

Apoptosis-associated speck-like protein containing a CARD (ASC) is a 22 kDa protein containing conserved PYD and CARD domains that belong to death-fold superfamily. Homotypic interactions between the domains occur via ...
Regulation of human BFK

Uğurlu, Serkan. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)

Bcl-2 protein family members are critical regulators for apoptosis. Reduced levels of apoptotic Bcl-2 family members are detected in gastrointestinal cancers which are responsible for a considerable part of the deaths from ...
Study of the polymerization dynamics of ASC and its domains

Kuzucu, Hulusi Onur. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2017., 2017.)

Apoptosis-associated speck-like protein containing a CARD (ASC) is a 22 kDa protein composed of two conserved death-fold domains, PYD and CARD, that act as an adaptor protein in in ammasomes, multimolecular complexes that ...
Two faces of ASC : central innate immunity adaptor ASC turns into melanoma ally and novel mechanism demistifying dsRNA induced NLRP3 inflammasome activation through Bax/Bak mediated cell death

Özkurede, Varol Ulaş. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)

In this study, by specifically focusing on the role of ASC in melanoma and NLRP3 activation in response to double stranded RNA, we try to provide answers to more general but basic questions: “How and why would cancer cells ...

Browsing Moleküler Biyoloji ve Genetik by Subject "Apoptosis."

Browsing Moleküler Biyoloji ve Genetik by Subject "Apoptosis."

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